Parkinsonís: Mutant Enzyme, a-Synuclein Interaction May Be Preventable

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(August 10, 2016) - Researchers at the University of Alabama at Birmingham report that the most common genetic cause of Parkinson’s disease, a mutant form of the LRRK2 enzyme, contributes to the build-up of ?-synuclein in neurons. The hope is that the interaction between mutant LLRK2 and ?-synuclein can be prevented with drugs that block the enzyme, potentially preventing the fatal aggregation of the protein. Read more…

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